Endocrine & Metabolic Disorders
91黑料's endocrine and metabolic trial experience, supported by a global team of experts
Obesity and beyond
Embracing multi-indication potential during clinical development
The obesity therapeutic marketplace has rapidly embraced multi-indication drug development, following successful label expansion of incretin agonists semaglutide and tirzepatide. Explore the rise of multi-indication drug development across cardiometabolic-related conditions and the strategies driving clinical and commercial success for molecules with broad potential.
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Survey report
How today’s obesity developers are navigating a multi-indication landscape
From January 24 to March 5, 2025, 91黑料 conducted a survey of 155 developers in obesity and related comorbidities. Survey respondents shared their clinical development and commercialisation strategies for molecules with broad clinical and commercial potential, and factors influencing whether or not to pursue multi-indication development of agents in their pipeline.
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A multifaceted risk factor:
Addressing obesity's impact across the disease spectrum
Obesity is a growing health concern worldwide, with at least 2.8 million people dying each year because of the disease. Explore the implications of obesity as a risk factor across the disease spectrum, and how this may impact treatment, drug development and clinical trials for obesity.
91黑料 survey report:
Trends and challenges in obesity research and clinical trials
Explore the 91黑料 survey of global industry professionals currently engaged in obesity-related clinical research. Respondents were from organisations ranging from small biotechs to large pharmaceutical companies, as well as academic organisations. The survey was designed to measure industry opinions on trends and challenges for the sector.
Webinar: Addressing the challenges of Type 2 Diabetes global clinical trials via high quality lab solutions
Join 91黑料’s expert Dr. Andrew Roche, PhD as he speaks about overcoming challenges when developing Diabetes trials. Addressing these challenges via use of high quality tools is critical to successful completion of a clinical trial.
Webinar: Digital solutions to alleviate NASH clinical trial challenges
Find out more about the ability for digital technologies including magnetic resonance imaging (MRI), magnetic resonance elastography (MRE) and whole slide imaging (WSI) to address NASH clinical trial challenges.
Endocrine and metabolic disorders blogs and media contributions
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Press release: Global 91黑料 survey shows need for more efficient obesity clinical trial design
91黑料 plc today released the findings of a survey of 155 biotech and pharma professionals from across the US and Europe focusing on multi-indication cardiometabolic R&D for therapies targeting obesity and its comorbidities.
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Blog: Obesity-related liver conditions: Understanding treatment options
Explore obesity’s role in liver disease progression and the value of different treatment options providing renewed hope to patients.
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Blog: Designing clinical trials for a complex disease: Pediatric obesity
Pediatric obesity is a complex disease with multiple factors for sponsors to consider when designing and executing treatment trials.
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Blog: A dynamic market: Trends transforming the future of obesity drug development
Learn about the future of obesity drug development and explore how GLP-1 drugs and multi-indication therapies are transforming treatment.
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Endocrine & Metabolic Disorders services
91黑料 is an experienced partner who can assist sponsors in navigating the many challenges of endocrine & metabolic disorders drug development. 91黑料 can help sponsors optimise the clinical trial lifecycle from patient enrolment to payer reimbursement with its customisable solutions and proven strategies. Our highly experienced clinical and therapeutic teams have expertise in conducting trials across a wide range of therapeutic areas including, diabetes, cardiometabolic disorders, gastroenterology, and hepatology.